INDICATIONS:
NAD has been shown to contribute to the following health benefits:
• Anti-aging at a cellular level
• Restores cellular energy, mitochondrial dysfunction
• DNA repair and protection
• Increased exercise performance and stamina
• Cognition and memory support; brain health
• Chronic Illnesses
• Neurodegenerative Diseases
• Autoimmune Diseases
• Drug Addiction and Detox
• Depression and Anxiety
• PTSD and Chronic Stress
• Metabolic Syndrome
INTRODUCTION:
Known as NAD+ Longevity Therapy or NAD+ Brain Restoration Therapy, NAD is the
acronym for nicotinamide adenine dinucleotide – a derivative of Vitamin B3. Found in virtually all living cells, NAD+ is essential to sustaining life. A fascinating aspect of NAD+ is
its dual role in protecting against factors that age us. This includes mitigating chemical
stress, environmental toxins, inflammation, DNA damage, and failing mitochondria (powerhouse of our cells.) At the same time, NAD+ also promotes longevity by facilitating
DNA repair and providing cellular benefits associated with caloric restriction and exercise.
NAD is also necessary for the production of a group of proteins called “Sirtuins” which
play a key role in aging, cell death, stress resistance, inflammation, energy efficiency, and
mitochondrial biogenesis (creation of more powerhouse cells.)
NAD+ AND AGING:
NAD+ levels markedly decline with age, creating an energy deficit that decreases the
body’s ability to retain youthful, healthy function. As we age our NAD+ levels significantly decrease and in advanced age, they plummet to near zero. To give you an idea how
impactful NAD+ can be, by age 50 a typical person may have only half the NAD+ they did
in youth and by age 80, they will only have about 1% of NAD reserves. The rigors of
modern day life are also taking a toll on our NAD levels. Even at a younger age, we are
seeing NAD Deficiency caused by stress, inflammation, diet, alcohol, and drug use, including prescription drugs. Deficiency of NAD+ predisposes us to accelerated aging and impedes our ability to fully benefit from nutrients, resveratrol and other important antioxidants that protect our cells from aging and disease. NAD plays such crucial roles in aging
that one day normal aging may be classified as “NAD+ deficiency syndrome.”
NAD+ AND CHRONIC ILLNESS:
NAD deficiency has also shown to have direct correlation with chronic illness. Low NAD
levels result in low levels of cellular energy, which is one of the primary factors of “mitochondrial dysfunction” – a condition that is implicated in a wide variety of chronic illnesses, including diabetes, autoimmune disorders, multiple sclerosis, and many more. Restoring NAD+ levels allows cells to return to full energy status, offering a possible way to
undo mitochondrial damage and the resulting chronic illness.
NAD+ AND BRAIN HEALTH:
One of the most impacted organs from NAD+ deficiency is the brain. NAD+ plays a vital
role in the brain by mediating brain aging and the tissue damage caused by various brain
illnesses. NAD+ helps to replenish the supply of neurotransmitters, improve cognitive
functioning, withdraw from addictive substances, overcome anxiety, depression, chronic or
acute stress, post-traumatic stress, CTE, and other conditions by giving the brain what it
needs to return to proper functioning. NAD+ has been shown to be effective with cases of
brain fog, cognitive impairment, and “chemo brain”. It has a powerful capacity to “reset”
the brain to its original set point.
ADMINISTRATION:
Using a direct IV infusion of pure compounded NAD+ from an FDA-registered pharmacy
is the most effective and efficient way of raising NAD+ levels. As NAD+ gains popularity
in the press and throughout the medical community, there are an increasing number of oral
NAD supplements available. However, oral supplements are not regulated and not very
effective at raising NAD levels.
NAD+ Therapy & Ketamine IV Therapy
Combination Treatment for Mental Health
and Overall Improved Quality of Life
By improving connections and messaging in the brain, we look at ketamine as a form of
liquid ambition and a way to improve people’s perspective on life. As Dr. Agin likes to
say, “when it comes to the puzzle of life, ketamine can help you find the pieces that fit correctly, as well as help you to identify the pieces that don’t fit or belong at all. Helping to
identify what is missing or what doesn’t belong in your life puzzle is the first step to living
a happier, healthier, smarter, and more fulfilled life.”
Ketamine IV Therapy
Ketamine is a medication that was developed in the 1960s and approved by the FDA in
1970 for use as a general anesthetic. Today, 50 years later, ketamine is still recognized as
one the safest and most widely used anesthetics in the world, including the United States,
for both humans and animals. Ketamine is also a medical therapy used to treat some mental conditions including anxiety, depression, PTSD and mood disorders. It is also used to
treat chronic pain conditions, as well as enhance cognition and memory.
Ketamine is very well researched and has recently been found to have powerful effects on
the way information travels through the brain. This communication enhancement is what
makes ketamine such an effective tool to not only fight depression, but also improve one’s
mood, memory, cognition and overall outlook on life. The medical community is also
looking at ketamine to help with the fight against cognitive diseases such as dementia and
Alzheimer’s Disease due to ketamine’s ability to produce new synapses in the brain. The
multiple beneficial actions of ketamine therapy can be seen both short term and long term.
For some patients the results are instant, while for others it can be more gradual, but either
way the results from treatment are real and can literally be life-changing for most patients.
In regards to depression, unlike traditional antidepressants that target the brain’s serotonin
and noradrenaline systems, ketamine appears to block a receptor called NMDA. Because
ketamine works on receptors and not on shifting hormone balances, the effects are dramatically faster. While traditional antidepressants can take anywhere from 4 to 8 weeks to start
taking effect, ketamine starts to work almost immediately, sometimes within minutes,
without the notorious side effects of psychiatric medications. Ketamine has remarkably
fast antidepressant effects and has been used for treatment-resistant depression, especially
in those patients with active and severe suicidal ideations. In fact, ketamine has shown reduction in depression in as little as 40 minutes. Ketamine therapy is given in doses much
lower than when it is used as an anesthetic and is administered very slowly through an intravenous (IV) infusion. This type of ketamine treatment does not induce general anesthesia and is not FDA approved for these particular conditions.
NAD+ Therapy
Research has shown that people with low levels of NAD+ are at a higher risk for developing problems related to addiction, depression, anxiety, other mental disorders and chronic
diseases. Recent studies have shown that enhancing NAD+ levels can profoundly reduce
oxidative cell damage in the brain reducing risks for disease. The actions of NAD+ make it
an excellent brain regeneration therapy through inflammation reduction and restoration of
neurotransmitters in your brain.
Neurotransmitter balance can improve symptoms of acute and chronic depression on its
own, or it can act as an ideal co-therapy alongside other traditional and non-traditional
treatments, including Ketamine Therapy. Stimulating production of important neurotransmitters such as dopamine, serotonin, and noradrenaline can directly improve mood,
brain function and also prevent future mental illness.
Understanding the role of mitochondrial function in psychiatric disorders may also lead to
a better understanding of how alternative therapies can provide substantial benefits when
compared to standard therapies for patients with mental illness.
Common Conditions for Ketamine/NAD+ Therapy:
• Depression
• Mood disorders
• Acute and chronic pain
• Fibromyalgia
• Obsessive-compulsive disorder (OCD)
• Post-traumatic stress disorder (PTSD)
• Anxiety Disorders
• Stress Disorders including improved response to stress
• Spectrum disorders including Rhett and Autism
• Neurodegenerative protection against dementia and Alzheimer’s Disease
• Cognitive enhancement and memory improvement
