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Ketamine IV Therapy is a safe and effective option to help with several conditions including:
- Depression/Low Mood - You do not need to be officially diagnosed with depression, anxiety etc, to receive and/or benefit from a KetamindTM treatment
- Anxiety/Chronic Stress
- Complex Regional Pain Syndrome (CRPS)
- Post-Traumatic Stress Disorder (PTSD)
- Fibromyalgia
- Phantom Limb
- Memory and Cognitive Issues
- Obsessive Compulsive Disorder (OCD)
- Mood Disorders
- Traumatic Brain Injuries (TBI)
- Post-concussive Syndrome
- Chronic Traumatic Encephalopathy (CTE)
- Neurodegenerative Diseases
What is Ketamine?
Ketamine is a medication that was developed in the 1960’s and approved by the FDA in 1970 for use as a general anesthetic. Ketamine is recognized as one the safest, most widely used anesthetic in the world and is still the #1 anesthetic used in every major US Hospital today.
What is Ketamine Infusion Therapy?
In 2019, the FDA approved ketamine nasal spray, under the brand name, Spravato for the treatment of treatment resistant depression. Since early 2006, Ketamine Infusion Therapy (KIT), although not FDA approved, has quickly become the go to treatment for treatment resistant depression and several other psychiatric disorders. New treatment options are extremely important as major depressive disorder cases are on the rise and is already the leading cause of disability worldwide. Furthermore, based on the medicine’s mechanism of action, it is also being used “off-label” to aid in the treatment and prevention of several other symptoms or diseases of the brain.
Unlike traditional antidepressants that target the brain’s serotonin and noradrenaline systems, ketamine appears to block a receptor called NMDA, which is activated by the neurotransmitter glutamate. Because ketamine works on receptors and not on shifting hormone balances, the results can be dramatically faster. While traditional antidepressants can take anywhere from 4 to 8 weeks to start taking effect, ketamine starts to work almost immediately, sometimes within minutes, without the notorious side effects of psychiatric medications.
How is Ketamine Therapy Administrated?
Ketamine Therapy is typically given as a series of intravenous (IV) treatments. The number of treatments is based on individual needs. Once the program is determined, a member of our team will insert an intravenous (IV) catheter into the hand or arm to allow for the administration of the ketamine. Depending on your health status, you may give other medications for nausea or other symptoms. Your vital signs, including blood pressure and pulse, will be checked prior to and during the treatment.
Each IV treatment usually lasts between 40-60 minutes. After the treatment ends, you will be monitored by a member of the treatment team for about 30 minutes to allow most of the medication’s effect to dissipate.
How Many Treatments Are Needed?
Every patient is different in regards to how many treatments are needed and how often. During your initial consultation with Dr. Agin, he will work with you to determine your anticipated number of treatments based on your symptoms and goals.
For mind and cognitive enhancement, treatments are weekly for 4 weeks and then monthly. All therapy duration may vary depending on the outcome of the initial intake and medical evaluation.

What conditions get better with Ketamine Therapy?
Ketamine Therapy is safe and effective to help in the treatment of several conditions including, several psychiatric conditions, posttraumatic stress disorder (PTSD), chronic pain and many other neurologic conditions. Ketamine has been helpful for several chronic pain disorders including complex regional pain syndrome (CRPS), ischemic limb pain, phantom limb pain, fibromyalgia, and other neuropathic conditions.
Ketamine is very well researched. There have been more than 50 clinical trials in the United States alone studying the use of ketamine for depression. Ketamine has remarkably fast antidepressant effects and has been used for treatment-resistant depression, especially in those patients with active and severe suicidal thoughts. Ketamine has shown reduction in depression and suicidal thoughts in as little as 40 minutes.
How Soon Can I Expect to Feel Results?
The most important opportunity for using KIT is on those with suicidal thoughts. Suicide rates are the highest they have been in our history and Ketamine has been shown to rapidly reduce suicidal thinking after only 1-2 treatments in a high percentage of patients. More than 70% of patients with treatment-resistant depression (including bipolar patients) experience some relief after a low-dose ketamine infusion and close to 50% can achieve remission. Similar success rates have been seen in returning combat veterans suffering from PTSD. It’s important to keep in mind, however, that the degree of relief and how quickly you feel the benefits can vary among patients due to other factors such as lifestyle and other health conditions. Some sufferers get only partial relief, some do not get relief until a second or third infusion, and a very small percentage do not respond to ketamine initially, but may still get some benefit in the following weeks to months.
Expectations for Ketamine Therapy
It is very important to understand the goals of Ketamine Therapy and what to expect when receiving a ketamine IV. Ketamine can be delivered in different doses and different settings depending on the clinic and physician administering the therapy. These differences can have a large impact on the experience and effectiveness of the treatment.
Priority You MD Ketamine Protocol
We have been utilizing Ketamine for several years and have developed a protocol that delivers the best therapeutic outcomes. The dosage of Ketamine that is needed to achieve desired effects also initiates the sensation of lightness or floating, dizziness, and mild euphoria – you are physically relaxed, but your mind is fully engaged. For this reason we place each patient in comfortable soft recliners in a dark, quite room. We apply a soft eye mask along with noise canceling headphones that stream pleasant music throughout the entirety of the IV therapy.
How do I get started?
Each patient is required to have an initial consultation with Dr. Agin. During this consultation, he will discuss your symptoms, your goals, and your expectations. He will also go through your medical history to determine if you are a good candidate for IV Ketamine Therapy.
To schedule your consultation, please call or text our office at 727-230-1438.

"Happiness is something that we create and is not guaranteed. Often times, we all need help or guidance to make life changes for our happiness. The chemicals and nerve pathways in the brain often become imbalanced or inefficient. This can leave us feeling hopeless and stuck without the motivation, energy, or ambition to take steps to find happiness. Ketamine, along with lifestyle changes, can provide the brain with a renewed energy and perspective that helps you find a path filled with opportunity and purpose. This program is a journey for those ready for self-exploration and enlightenment. By helping with motivation, depression, anxiety, you can break free from the past and find a new path that guides you to be the best version of yourself and live your best life possible."